Publications
2024
1. Nakahata, D. H.; Kanavos, I.; Zubiria-Ulacia, M.; Inague, A.; Salassa, L.; Lobinski, R.; Miyamoto, S.; Mattin Matxain, J.; Ronga, L.; de Paiva, R. E. F.; “Gold-promoted biocompatible selenium arylation of small molecules, peptides and proteins”, Chem. Eur. J., 2024, e202304050; ChemRxiv.
2023
8. Aboudzadeh, M. A.; Rodríguez-Fanjul, V.; Terenzi, A.; Gónzalez de San Román, E.; Miranda, J. I.; Pizarro, A. M.; Salassa, L.; Barroso-Bujans, F.; “Synthesis and Characterization of a Luminescent Cyclic Poly(ethylene oxide)−Polypyridyl Ruthenium Complex”, ACS Macro Lett. 2023, 12, 999-1004.
7. Azpitarte, O.; Zudaire, A.; Uranga, J.; Lopez, X.; Salassa, L.; Formoso, E.; Rezabal, E.; “One- and Two- Electron Reductions in MiniSOG and theirImplication in Catalysis”, ChemPhysChem2023, e202300091; ChemRxiv.
6. Castillo Pacheco, S. F.; Moran, M. J.; Santos, J. I.; Salassa, L; López-Gallego, F.; “Chemoenzymatic oxidation of diols catalyzed by coimmobilized flavins and dehydrogenases”, ChemCatChem2023, e202300140; ChemRxiv.
5. Sánchez-Camacho, J.; Infante-Tadeo, S.; Carrasco, A. C.; Scoditti, S.; Martínez, A.; Barroso-Bujans, F.; Sicilia, E.; Pizarro, A. M.; Salassa, L.; “Flavin-Conjugated Pt(IV) Anticancer Agents”, Inorg. Chem., 2023, 62, 14, 5644–5651; ChemRxiv.
4. Mazzei, L.F.; Gurruchaga-Pereda, J.; Martínez, A.; Calvo Martínez, J.; Salassa, L.; Cortajarena, A. L.; “Engineered flavoproteins as bioorthogonal photo-triggers for the activation of metal-based anticancer prodrugs”, Chem Commun, 2023, 59, 4754-4757.
3. Orrego, A.H.; Rubanu, M.G.; López, I. L.; Andrés-Sanz, D.; García-Marquina, G.; Pieslinger, G. E.; Salassa, L.; López-Gallego, F.; “ATP-independent and cell-free biosynthesis of β-hydroxy acids using vinyl esters as smart substrates”, Angew. Chem. Int. Ed., 2023, e202218312.
2. Canil, G.; Gurruchaga-Pereda, J.; Braccini, S.; Marchetti, L.; Funaioli, T.; Marchetti, F.; Pratesi, A.; Salassa, L.; Gabbiani, C.; "Synthesis, Characterization and Photoactivation Studies on the Novel Pt(IV)-Based [Pt(OCOCH3)3(phterpy)] Complex", Int. J. Mol. Sci., 2023, 24, 1106.
1. López-Gallego, F.; Salassa, L.; Catalysis toward metal-based substrates: A new prospect for inorganic chemistry, Chem Catalysis, 2023, 3, 1–14.
2022
3. Scoditti, S.; Dabbish, E.; Pieslinger, G. E.; Rezabal, E.; Lopez, X.; Sicilia, E.; Salassa, L.; Flavin-Mediated Photoactivation Of Pt(IV) Anticancer Complexes: Computational Insights On The Catalytic Mechanism, Phys. Chem. Chem. Phys., 2022, 24, 5323-5329.
2. Velasco-Lozano, S.; Alonso-de Castro, S.; Sanchez-Cano, C.; Benítez-Mateos, A. I.; López-Gallego, F.; Salassa, L.; “Metal substrate catalysis in the confined space for platinum drug delivery”, Chem. Sci., 2022, 13, 59-67.
1. Farley, S. J.; Salassa, L.*; Pizarro, A. M.; Sadler, P. J.*; Photoactive platinum(II) azopyridine complexes”, Photochem. Photobiol., 2022, 98, 92-101.
2021
5. Terenzi, A.; La Franca, M.; van Schoonhoven, S; Panchuk, R.; Martínez, A.; Heffeter, P.; Gober, R.; Pirker, C.; Vician, P.; Kowol, C. R.; Stoika, R.; Salassa, L.; Rohr, J.; Berger, W.; "Landomycins as glutathione-depleting agents and natural fluorescent probes for cellular Michael adduct-dependent quinone metabolism", Commun. Chem. 2021, 4, 162.
4. Xue, X.; Fu, Y.; Liang He, Salassa, L.; He, L.-F.; Hao, Y.-Y.; Koh, M. J.; Soulie, C.; Needham, R. J.; Habtemariam, A.; Garino, C.; Lomachenko, K. A.; Su, Z.; Qian, Y.; Paterson, M. J.; Mao, Z.-W-; Liu, H.-K.; Sadler, P. J.; “Photoactivated Osmium Arene Anticancer Complexes”, Inorg. Chem. 2021, 60, 17450–17461.
3. Shaili, E.; Romero, M. J.; Salassa, L.; Woods, J. A.; Butler, J. S.; Romero-Canelón, I.; Clarkson, G.; Habtemariam, A.; Sadler P. J.; Farrer, N. J.; “Platinum(IV)-azido monocarboxylato complexes are photocytotoxic under irradiation with visible light”, Dalton Trans., 2021, 50, 10593–10607.
2. Salassa, G.; Salassa, L.; “Unconventional Approaches in Coordination Chemistry and Organometallic Reactivity”, ACS Omega, 2021, 6, 11, 7240–7247.
1. Gurruchaga-Pereda, J.; Martínez-Martínez, V.; Formoso, E.; Azpitarte, O.; Rezabal, E.; Lopez, X.; Garino, C.; Mancin, F.; Cortajarena, A. L.; Salassa, L.; “Enhancing The Photocatalytic Conversion Of Pt(IV) Substrates By Flavoprotein Engineering”, J. Phys. Chem. Lett. 2021, 12, 4504–4508; ChemRxiv.
2020
3. Mazzei, L.F.; Martínez, A.; Trevisan, L.; Rosa-Gastaldo, D.; Cortajarena, A. L.; Mancin, F.; Salassa, L.; “Toward Supramolecular Nanozymes For The Photocatalytic Activation of Pt(IV) Anticancer Prodrugs”, Chem. Commun., 2020, 56, 10461-10464.
2. Guarra, F.; Terenzi, A.; Pirker, C.; Passannante, R.; Baier, D.; Zangrando, E.; Gómez, V.; Biver, T.; Gabbiani, C.; Berger, W.; Llop, J.; Salassa, L.; “124I-Radiolabeling of a Au(III)-NHC Complex for in Vivo Biodistribution Studies”, Angew. Chem. Int. Ed., 2020, 59 17130-17136; ChemRxiv.
1. Gurruchaga-Pereda, J.; Martínez-Martínez, V.; Rezabal, E.; Lopez, X.; Garino, C.; Mancin, F.; Cortajarena, A. L.; Salassa, L.; “Flavin Bioorthogonal Photocatalysis Toward Platinum Substrates”, ACS Catal. 2020, 10, 187-196.
2019
6. Shaili, E.; Salassa, L.; Woods, J. A.; Clarkson, G.; Sadler, P. J.; Farrer, N. J.; “Platinum(IV) dihydroxido diazidoN-(heterocyclic)imine complexes are potently photocytotoxicwhen irradiated with visible light”, Chem. Sci. 2019, 10, 8610–8617.
5. Benitez-Mateos, A. I.; Mehravar, E.; Velasco-Lozano, S.; Tomovska, R.; Salassa, L.; López-Gallego, F.; “Selective Immobilization of Fluorescent Proteins for the Fabrication of Photoactive Materials”, Molecules, 2019, 24, 2775.
4. Hager, L. A.; Mokesch, S.; Kieler, C.; Alonso-de Castro, S.; Baier, D.; Roller, A. Kandioller, W.; Keppler, B. K.; Berger, W.; Salassa, L.; Terenzi, A.; “Ruthenium-arene complexes bearing naphthyl-substituted 1,3-dioxoindan-2-carboxamides ligands for G-quadruplex DNA recognition”, Dalton Trans., 2019, 48, 12040-12049.
3. Gurruchaga-Pereda, J.; Martínez, Á.; Terenzi, A.; Salassa, L.; "Anticancer Platinum Agents and Light", Inorg. Chim. Acta, 2019, 495, 118981.
2. Alonso-de Castro, S.; Ruggiero, E.; Lekuona Fernández, A.; Cossío, U.; Baz, Z.; Otaegui, D.; Gómez-Vallejo, V.; Padró, D.; Llop, J.; Salassa, L.; “Functionalizing NaGdF4:Yb,Er Upconverting Nanoparticles with Bone-Targeting Phosphonate Ligands: Imaging and In Vivo Biodistribution”, Inorganics, 2019, 7, 60.
1. Alonso-de Castro, S.; Terenzi, A.; Gurruchaga-Pereda, J.; Salassa, L.; “Catalysis Concepts In Medicinal Inorganic Chemistry”, Chem. Eur. J., 2019, 25, 6651-6660.
2018
3. Cubo, L.; Parro, T.; Carnero, A.; Salassa, L.; Matesanz, A. I.; Quiroga, A. G.; “Synthesis, Reactivity Studies, and Cytotoxicity of Two trans-Iodidoplatinum(II) Complexes. Does Photoactivation Work?”, Inorganics, 2018, 6, 127.
2. Alonso-de Castro, S.; Terenzi, A.; Hager, S.; Englinger, B.; Faraone, A.; Calvo Martínez, J.; Galanski, M.; Keppler, B. K.; Berger, W.; Salassa, L.; “Biological activity of Pt(IV) prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis”, Sci. Rep. 2018, 8, 17198.
1. Alonso-de Castro, S.; Cortajarena, A. L.; López-Gallego, F.; Salassa, L.; "Bioorthogonal Catalytic Activation Of Pt And Ru Anticancer Complexes By FAD And Flavoproteins", Angew. Chem. Int. Ed., 2018, 57, 3143 –3147.
2017
4. Alonso-de Castro, S.; Ruggiero, E.; Ruiz-de-Angulo, A.; Rezabal, E.; Mareque-Rivas, J. C.; Lopez, X.; López-Gallego, F.; Salassa, L.; “Riboflavin As Bioorthogonal Photocatalyst For The Activation Of A Pt(IV) Prodrug”, Chem. Sci., 2017, 8, 4619-4625.
3. Garmendia, S.; Mantione, D.; Alonso-de Castro, S.; Jehanno, C.; Lezama, L.; Hedrick, J. L.; Mecerreyes, D.; Salassa, L.; Sardon, H.; “Polyurethane based organic macromolecular contrast agent (PU-ORCA) for magnetic resonance imaging”, Polym. Chem., 2017, 8, 2693-2701.
2. Smith, N. A.; Zhang, P.; Greenough, S. E.; Horbury, M. D.; Clarkson, G. J.; McFeely, D.; Habtemariam, A.; Salassa, L.; Stavros, V. G.; Dowson, C.; Sadler, P. J.; “Photoactivatable Ruthenium(II)-isoniazid Complex for Combatting Mycobacterium Tuberculosis Antimicrobial Resistance”, Chem. Sci., 2017, 8, 395-404.
1. Smith, N. A.; Zhang, P.; Salassa, L.; Habtemariam, A.; Sadler, P. J.; “Synthesis, characterisation and dynamic behavior of photoactive bipyridyl ruthenium(II)-nicotinamide complexes”, Inorg. Chim. Acta, 2016, 454, 240-246.
2016
4. Ruggiero, E.; Alonso-de Castro, S.; Habtemariam, A.; Salassa, L.; “Upconverting Nanoparticles For The Near Infrared Photoactivation Of Transition Metal Complexes: New Opportunities And Challenges In Medicinal Inorganic Photochemistry”, Dalton Trans., 2016, 45, 13012-13020.
3. Fu, Y.; Romero, M. J.; Salassa, L.; Cheng, X.; Habtemariam, A.; Clarkson, G. J.; Prokes, I.; Rodger, A.; Costantini, G.; Sadler, P. J.; “Os2-Os4 switch controls DNA knotting and anticancer activity”, Angew. Chem. Int. Ed., 2016, 128, 9055-9058.
2. Ruggiero, E.; Garino, C.; Mareque-Rivas, J. C.; Habtemariam, A.; Salassa, L.; “Upconverting Nanoparticles Prompt Remote Near-Infrared Photoactivation of Ru(II)–Arene Complexes”, Chem. Eur. J., 2016, 22, 2801-2811.
1. Garino, C.; Terenzi, A.; Barone, G.; Salassa, L.; “Teaching Inorganic Photophysics and Photochemistry with Three Ruthenium(II) Polypyridyl Complexes: A Computer-Based Exercise:”, J. Chem. Educ., 2016, 93, 292-298.
2015
7. Navas, F.; Perfahl, S.; Garino, C.; Salassa, L.; Novakova, O.; Navarro, C.; Bednarski, P. J.; Malina, J.; Quiroga, A. G.; “Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light”, J. Inorg. Biochem., 2015, 211-218.
6. Hernández-Gil, J.; Cobaleda-Siles, M.; Zabaleta Azpiroz, A.; Salassa, L.; Calvo, J.; Mareque-Rivas, J. C.; “An Iron Oxide Nanocarrier Loaded with a Pt(IV) Prodrug and Immunostimulatory dsRNA for Combining Complementary Cancer Killing Effects”, Adv. Healthcare Mater., 2015, 4, 1034-1043. (Journal Internal Cover Picture)
5. Habtemariam, A.; Garino, C.; Ruggiero, E.; Alonso-de Castro, S.; Mareque-Rivas, J. C.; Salassa, L.; “Photorelease of Pyridyl Esters in Organometallic Ru(II) Arene Complexes”, Molecules, 2015, 20, 7276-7291. (Invited, Open Access)
4. Betanzos-Lara, S.; Chmel, N. P.; Zimmerman, M. T.; Barrón-Sosa, L. R.; Garino, C.; Salassa, L.; Rodger, A.; Brumaghim, J.; Gracia-Mora, I.; Barba-Behrens, N.; “Redox-active and DNA-binding coordination complexes of clotrimazole”, Dalton Trans., 2015, 44, 3673-3685.
3. Ruggiero, E.; Hernández-Gil, J.; Mareque-Rivas, J. C.; Salassa, L.; “Near Infrared Activation of an Anticancer Pt(IV) Complex by Tm-Doped Upconverting Nanoparticles”, Chem. Commun., 2015, 51, 2091-2094.
2. Laskay, Ü. A.; Tsybin, Y. O.; Garino, C.; Salassa, L.; Casini, A.; “Gold fingers motives formation studied via high-resolution mass spectrometry and in-silico methods”, Chem. Commun., 2015, 51, 1612-1615.
1. Méndez-Ramos, J.; Acosta-Mora, P.; Ruiz-Morales, J. C.; Sierra, M.; Redondas, A.; Ruggiero, E.; Salassa, L.; Borges, M.E.; Esparza, P.; “Rare-earth doped colour tuneable up-conversion ZBLAN phosphor for enhancing photocatalysis”, Opt. Mat., 2014, 41, 98-103.
2014
7. Ruggiero, E.; Alonso-de Castro, S.; Habtemariam, A.; Salassa, L.; “The Photochemistry of Transition Metal Complexes and Its Application in Biology and Medicine”, Structure and Bonding, 2014, 165, 69-108.
6. Mari, C.; Pierroz, V.; Rubbiani, R.; Patra, M.; Hess, J.; Spingler, B.; Oehninger, L.; Schur, J.; Ott, I.; Salassa, L.; Ferrari S.; Gasser, G.; “DNA intercalating Ru(II) Polypyridyl Complexes as effective Photosensitizers in Photodynamic Therapy”, Chem. Eur. J., 2014, 20, 14421-14436.
5. Infante, I.; Azpiroz, J. M.; Gomez Blanco, N.; Ugalde, J. M.; Mareque-Rivas, J. C.; Salassa, L.; “Quantum Dot Photoactivation of Pt(IV) Anticancer Agents: Evidence of an Electron Transfer Mechanism Driven by Electronic Coupling”, J. Phys. Chem. C, 2014, 118, 8712-8721.
4. Rubbiani, R.; Salassa, L.; de Almeida, A.; Casini, A.; Ott, I.; “Gold(I) N-heterocyclic carbene complexes with phosphane ligands are inhibitors of TrxR and PARP-1 with cytotoxic properties”, ChemMedChem, 2014, 9, 1205-1210. (V.I.P. Paper).
3. Borfecchia, E.; Garino, C.; Gianolio, D.; Salassa, L.; Gobetto, R.; Lamberti,C.; "Monitoring excited state dynamics in cis-[Ru(bpy)2(py)2]2+ by ultrafast synchrotron techniques", Cat. Today, 2014, 229, 34-35.
2. Garaikoetxea Arguinzoniz, A.; Ruggiero, E.; Habtemarian, A.; Hernández-Gil, J.; Salassa, L.; Mareque-Rivas, J. C.; “Light harvesting and photoemission by nanoparticles for photodynamic therapy”, Part. Part. Syst. Charact., 2014, 1, 46-75. (Journal Cover)
1. Ruggiero, E.; Habtemariam, A.; Yate, L.; Mareque-Rivas, J. C.; Salassa, L.; “Near Infrared Photoactivation of a Ru Polypyridyl Complex by Upconverting Nanoparticles”, Chem. Commun., 2014, 50, 1715-1718.
2013
12. Fu, Y.; Soni, R.; Romero, M. J.; Pizarro, A. M.; Salassa, L.; Clarkson, G. J.; Hearn, J. M.; Habtemariam, A.; Wills, M.; Sadler, P. J.; “Mirror-Image Organometallic Osmium Arene Iminopyridine Halido Complexes Exhibit Similar Potent Anticancer Activity”, Chem. Eur. J., 2013, 19, 15199-15209.
11. Sharmin, A.; Salassa, L.; Rosenberg, E.; Ross, J. B. A.; Abbott, G.; Black, L.; Terwilliger, M.; “Photophysical Studies of Bioconjugated Ruthenium Metal Ligand Complexes Incorporated in Phospholipid Membrane Bilayers”, Inorg. Chem. 2013, 52, 10835-10845.
10. Lomachenko, K. A.; Garino, C.; Gallo, E.; Gianolio, D.; Gobetto, R.; Glatzel, P.; Smolentsev, N.; Smolentsev, G.; Soldatov, A. V.; Lamberti C.; Salassa L.; “High energy resolution core-level X-ray spectroscopy for electronic and structural characterization of osmium compounds”, Phys. Chem. Chem. Phys., 2013, 15, 16152-16159.
9. Maldonado, C. R.; Salassa, L.; Gomez-Blanco N.; Mareque-Rivas, J. C.; “Nano-functionalization of metal complexes for molecular imaging and anticancer therapy”, Coord. Chem. Rev., 2013, 257, 2668-2688.
8. Zhao, Y.; Woods, J. A.; Farrer, N. J.; Robinson, K. S.; Pracharova, J.; Kasparkova, J.; Novakova, O.; Li, H.; Salassa, L.; Pizarro, A. M.; Clarkson, G. J.; Song, L.; Brabec, V.; Sadler, P. J.; “Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts”, Chem. Eur. J., 2013, 19, 9578-9591.
7. Tolia, C.; Papadopoulos, A. N.; Raptopoulou, C. P.; Psycharis, V.; Garino, C.; Salassa, L.; Psomas G. “Copper(II) interacting with the non-steroidal antiinflammatory drug flufenamic acid: Structure, antioxidant activity and binding to DNA and albumins”, J. Inorg. Biochem., 2013, 123, 53-65.
6. Al-Jibori, S.A.; Al-Nassiry, A. I. A.; Hogarth, G.; Salassa, L., “Platinum and palladium bis(diphenylphosphino)ferrocene (dppf) complexes with heterocyclic N-acetamide ligands: Synthesis and molecular structures of [MCl(sac)(κ2-dppf)] (M = Pt, Pd, sac = saccharinate), [PtCl(ata)(κ2-dppf)] and [Pt(ata)2(κ2-dppf)] (ataH = N-(2-thiazolyl)acetamide)”, Inorg. Chim. Acta, 2013, 398, 46-53.
5. Gianolio, D.; Borfecchia, E.; Garino, C.; Ruiu, T.; Lamberti, C.; Salassa, L. “The Use of Differential EXAFS Analysis for the determination of Small Structural Differences between two closely-related Ruthenium Complexes”, J. Phys.: Conf. Series, 2013, 430, 012125.
4. Borfecchia, E.; Garino, C.; Salassa, L.; Lamberti, C., “Synchrotron ultrafast techniques for photoactive transition metal complexes”, Phil. Trans. R. Soc. A, 2013, 20120132.
3. Garino, C.; Salassa, L. “The Photochemistry of Transition Metal Complexes Using DFT”, Phil. Trans. R. Soc. A, 2013, 20120134.
2. Borfecchia, E.; Garino, C.; Salassa, L.; Ruiu,T.; Gianolio, D.; Zhang, X.;Attenkofer, K.; Chen L. X.;Gobetto, R.; Sadler, P. J.; Lamberti, C. “Picosecond Photoinduced Ligand Dissociation from cis-[Ru(bpy)2(py)2]2+: X-Ray Transient Absorption Structural Characterization of a Triplet Excited State”, Dalton Trans., 2013, 42, 6564-6571.
1. Romero, I.; Salassa, L.; Sadler, P. J. “The Contrasting Activity of Iodido versus Chlorido Ruthenium and Osmium Arene Azo- and Imino-pyridine Anticancer Complexes: Control of Cell Selectivity, Cross-resistance, p53 Dependence and Apoptosis Pathway”, J. Med. Chem., 2013, 56, 1291-1300.
2012
5. Garino, C.; Gallo, E.; Smolentsev, N.; Glatzel, P.; Gobetto, R.; Lamberti, C.; Sadler, P. J.; Salassa, L. “Resonant X-Ray Emission Spectroscopy Reveals d–d Ligand-Field States Involved in the Self-Assembly of a Square-Planar Platinum Complex”, Phys. Chem. Chem. Phys., 2012, 14, 15278-15281. (Journal Cover Picture, ESRF highlights 2012)
4. Ragazzon, G.; Bratsos, I.; Alessio, E.; Salassa, L.; Habtemariam, A.; McQuitty, R. J.; Clarkson, G. J.; Sadler, P. J. “Design of Photoactivatable Metallodrugs: Selective and Rapid Light-induced Ligand Dissociation from Half-Sandwich [Ru([9]aneS3)(N–N')(py)]2+ Complexes”, Inorg. Chim. Acta, 2012, 393, 230-238. (Invited Manuscript)
3. Westendorf, A. F.; Woods, J. A.; Korpis, K.; Farrer, N. J.; Salassa, L.; Robinson, K.; Appleyard, V.; Murray, K.; Grünert, R.; Thompson, A.; Sadler, P. J.; Bednarski, P. J. “Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light activated anti-tumor platinum complex that kills human cancer cells by an apoptosis independent mechanism”, Mol. Cancer Ther., 2012, 11, 1894-1904.
2. Betanzos-Lara, S.; Salassa, L.; Habtemariam, A.; Novakova, O.; Pizarro, A. M.; Clarkson, G. J.; Liskova, B.; Brabec, V.; Sadler, P. J. "Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes", Organometallics, 2012, 31, 3466-3479. (Journal Cover Picture)
1. Hossain, Md. I.; Sikder, Md. D. H.; Ghosh, S.; Hogarth, G.; Kabir, S. E.; Salassa, L. "Reactivity of Triruthenium Furyne and Thiophyne Clusters: Multiple Additions of Thiolato and Selenolato Ligands through Oxidative Addition of S─H and Se─H Bonds", Organometallics, 2012, 31, 2546-2558.